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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

A. A. Moosavi-Movahedi

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Sep 2026

Mechanistic insights into the inhibition of insulin amyloidogenesis and associated toxicity by the p.M14L variant of exenatide.

Insulin fibrillation and the subsequent formation of toxic amyloid aggregates are significant challenges in therapeutic development and are associated with cellular proteotoxicity. In this research, we explored how the p.M14L exenatide variant affects the formation of insulin amyloid fibrils. Applying a combination of...

Zahra Bahrami, Mohammad Rajab Shalgahi, M. Shahsavani et al. · 0 citations
Open access Aug 2026

Cold stimulus during the fibrillation lag phase induces molecularly distinct amyloid strains

The results show how amyloid polymorphs could differentially modulate pathogenicity and the importance of environmental conditions on the molecular features of amyloid nucleation may be critical for design and stability of future protein biologics beyond therapeutic insulin.

Elnaz Hosseini, Saeid Hadi Alijanvand, Y. Kan et al. · 0 citations

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