Detoxification as metabolic rewiring: carbon and redox recovery from lignocellulosic inhibitors in biorefinery hosts
The pretreatment process of lignocellulosic biomass results in the formation of inhibitory by-products such as furan aldehydes, phenolics, and weak acids that hinder the process of microbial fermentation. Historically, the detoxification process has been regarded as an exercise in waste management, resulting in carbo...