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Open access Sep 2026

Mitotically driven cytoskeletal reorganization governs zebrafish left-right organizer detachment from EVL and lumen morphogenesis.

Left-right asymmetry in vertebrate embryos is established by the left-right organizer (LRO), with the zebrafish Kupffer's vesicle (KV) providing a tractable model for studying de novo epithelial morphogenesis. During KV formation, dorsal forerunner cells (DFCs) initially form polarized attachments to the enveloping lay...

Yi-Ling Lan, Yan Wu, Miriam Athena Allred et al. · 1 citation

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