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A. Affinito

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Open access Sep 2026

Aptamer-guided delivery of miR-126 suppresses glioblastoma stem-like cell invasion and tumor progression

Glioblastoma, IDH-wildtype (GBM) is the most common and aggressive primary brain tumor in adults, with a median overall survival of 15–18 months. New therapeutic targets are needed to improve patients’ prognosis. Due to their powerful regulatory capabilities, miRNAs could be possible candidate targets. MiR-126 is consi...

G. Castellani, M. Buccarelli, A. Affinito et al. · 0 citations
Review Open access Aug 2026

Advances in Aptamer Diagnostics Targeting Non-Small-Cell Lung Cancer: A Systematic Review

A review aimed at summarizing current knowledge on the new promising DNA and RNA aptamer-based molecules for NSCLC diagnosis showed that several DNA and RNA aptamers are promising diagnostic tools for NSCLC management.

Lisa Agnello, Ilaria Leone, A. Affinito et al. · 0 citations

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