Drug Repurposing of Verapamil for Radiation-Induced Enteropathy: Regulation of 5-LOX, Nrf2, and Intestinal Barrier Function
Investigating the protective effects of verapamil on radiation-induced small-intestinal injury in rats found it attenuated radiation-induced histopathological injury and was associated with favorable modulation of TNF-α, 5-LOX, Nrf2, and ZO-1 levels.