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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

A. Altharawi

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Sep 2026

Synthesis of Novel Pyrazolopyranopyrimidine Acyclic Nucleosides Disubstituted at N2/C5 as Potential Anti-SARS-CoV-2 Inhibitors: Structural Characterization, and In Silico Studies

Novel pyrazolo[4′,3′:5,6]pyrano[2,3-d]pyrimidine acyclonucleosides bearing HBG-derived pseudosugar moieties bearing HBG-derived pseudosugar moieties as potential antiviral agents targeting key SARS-CoV-2 proteins are designed and synthesized.

Ezaddine Irrou, Younesse Ait Elmachkouri, Rakibul Islam et al. · 0 citations
Aug 2026

Synthesis and in silico evaluation of novel hybrid 1,4-benzothiazine-1,1-dioxide-bis(1,2,3-triazole) derivatives as potential SRC kinase inhibitors via 1,3-dipolar cycloaddition.

Herein, we report the synthesis of new 1,4-benzothiazine-1,1-dioxide derivatives bearing bis(1,2,3-triazole) moieties via click chemistry in good to high yields and fully characterized by 1H NMR, 13C NMR and HRMS. The compounds were evaluated using a combined in silico approach, including physicochemical, pharmacokinet...

Ezaddine Irrou, Chagaleti Bharath Kumar, Y. Riadi et al. · 0 citations

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