Author

A. Andries

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Open access Sep 2026

Disease progression Mendelian randomization of risk factors for kidney function decline in chronic kidney disease and the general population

Introduction With limited treatment options, identifying risk factors for chronic kidney disease (CKD) disease progression is an important aspect of CKD management. Novel approaches for correcting case-only genome-wide association studies (GWAS) for index event bias and the availability of large GWAS conducted in peopl...

A. Andries, V. Walker, A. Briasouli et al. · medRxiv · 0 citations

Open access Jul 2026

Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms

This study provides the most comprehensive assessment of IBS genetics to date, demonstrating reproducible polygenic inheritance and linking IBS risk to convergent neurogastrointestinal and novel cardiometabolic mechanisms, highlight specific biological pathways and actionable mechanisms and outline translational opport...

Biagio Di Lorenzo, L. Camargo Tavares, Cristian Díaz-Muñoz et al. · Gut · 0 citations