Indole alkaloids are a structurally diverse class of natural compounds known for their potent anticancer properties, including the ability to induce apoptosis and inhibit cell proliferation and metastasis. This study aimed to evaluate the cytotoxic potential of 20 indole alkaloids against breast cancer cell lines, inve...
Rollando Rollando, V. Kharisma, A. Ansori· Indonesian Journal of Pharma...· 0 citations
COVID-19, caused by SARS-CoV-2, depends on its main protease (Mpro) for viral replication. This study evaluated the potential of polyphenolic compounds from Phoenix dactylifera as Mpro inhibitors using molecular docking, molecular dynamics (MD) simulations, and ADMET profiling. Three ligands - flavoxanthin, violaxanthi...
G. M. Gholam, R. A. P. Irsal, F. R. Mahendra et al.· Letters in Applied NanoBioSc...· 0 citations
The findings underscore the promising pharmacological potential of L. cernuum and highlight the need for rigorously designed studies, particularly well-controlled clinical trials and mechanistic investigations, to validate its efficacy and safety and to inform its rational development as a therapeutic agent.
Rollando Rollando, Dodi Iskandar, V. Kharisma et al.· Majalah Obat Tradisional· 0 citations
It is suggested that shallot-derived organosulfur compounds, especially γ-glutamyl-S-propenylcysteine, exhibit potential for interaction with H5N1 viral targets and may warrant further investigation as antiviral candidates.
Rangga Adhi Prastika, Alifaghi Pahlevi Ervianto Putra, Muhammad Alesha Fadhana et al.· Frontiers in Virology· 1 citation
Results indicate that MFEO disrupts multiple life stages through combined chemosensory interference, eggshell damage and neurotoxic action, and warrants further investigation as a botanical candidate for integrated vector management, potentially offering an alternative to some conventional neurotoxic insecticides.
P. H. Hamid, A. Ansori, M. A. Herdiansyah et al.· Current Research in Parasito...· 0 citations
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