BACKGROUND
T cells are often enriched at barrier tissues, yet little is known of their roles in barrier sensing and relevance to associated disease. CD1a is a Major Histocompatibility Complex class I-like molecule expressed by Langerhans cells, which forms complexes with lipid antigens to facilitate recognition by non-...
Rosana Ottakandathil Babu, Janina Nahler, K. Dooley et al.· British Journal of Dermatolo...· 0 citations
Early immune processes in idiopathic pulmonary fibrosis (IPF) are poorly defined. Here, we integrate single-cell transcriptomics of lung digests and bronchoalveolar-lavaged cells (n = 108 patients), subcellular-resolution tissue spatial transcriptomics, and single-cell phospho-CyTOF of blood cells to define myeloid sta...
V. Nathwani, P. Weeratunga, J. Woo et al.· Cell Reports· 0 citations
Spatial transcriptomics (ST) maps gene expression within intact tissues, but its cost and technical complexity limit broad adoption. A growing body of deep-learning methods now seeks to infer ST directly from routine histology images, especially hematoxylin and eosin (H&E)-stained slides, with the aim of turning archiv...
Ke-Xin Xu, H. Koohy, A. Antanaviciute· EXO· 0 citations
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