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Open access Sep 2026

Insomnia symptom severity predicts blunted cortisol reactivity to a psychosocial stressor.

Insomnia is characterized by a state of hyperarousal, sometimes seen as increases in hypothalamic-pituitary-adrenal (HPA) axis activity (e.g., greater cortisol secretion). The evidence for the association between insomnia symptoms and HPA-axis functioning, however, is surprisingly mixed. Moreover, few studies have inve...

Ivan Vargas, Harrison Dickens, Abigail Vance et al. · 0 citations

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