Association of IL-8 rs4073 -251T>A gene polymorphism with diabetic nephropathy in patients with type 2 diabetes mellitus.
BACKGROUND Diabetic nephropathy (DN) is one of the most common microvascular complications of type 2 diabetes mellitus (T2DM) and a leading cause of chronic kidney disease worldwide. Inflammatory pathways play a key role in the pathogenesis and progression of DN. Interleukin-8 (IL-8), a pro-inflammatory cytokine involv...