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Author

A. Ayeleso

2 papers indexed here

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Review Open access Oct 2026

Targeting the IRE1α/XBP1 pathway in type 2 diabetes mellitus: from ER stress signaling to therapeutic opportunity

To respond to protein misfolding in the endoplasmic reticulum (ER), cells trigger the unfolded protein response (UPR) to re-establish proteostasis. However, unresolved UPR results in chronic ER stress, which is critical to the development and advancement of type 2 diabetes mellitus (T2DM), a multifactorial disease whos...

O. T. Obafemi, A. Ayeleso, B. E. Ekundayo et al. · 0 citations
2025

Influence of quercetin on oxidative stress biomarkers and neurotoxic enzyme dysregulation in in vitro and ex vivo studies

Oxidative stress and impaired neurotoxic enzymes have been implicated in the etiology of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, that are characterized by cognitive and motor deficits. Quercetin is a natural flavonoid found in a wide range of plants and exhibits strong antioxi...

Clinton Ayodeji Akanbi, P. O. Ayeni, M. Ayomipo et al. · 0 citations

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