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Author

A. Badawy

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Aug 2026

Unexpected roles of aromatic ring-cleaving dioxygenases in oxygen-heterocycle degradation: Functional diversity, gene redundancy, and ecological implications.

This work demonstrates that classical aromatic ring-cleaving dioxygenases mediate the cellular cleavage of 2-hydroxytetrahydrofuran (2-OH THF), a key intermediate in THF metabolism, to yield 4-hydroxybutyric acid (GHB), and establishes a novel catalytic route for cyclic ether degradation in aquatic systems.

Hao Ren, Siqing Fan, Yiran Yin et al. · 0 citations
Aug 2026

Statistical optimization of extracellular antimicrobial metabolite production by Streptomyces enissocaesilis ASB isolate targeting multidrug-resistant pathogens

Findings highlight S. enissocaesilis ASB as a promising source of extracellular bioactive metabolites and provide a foundation for future studies involving compound purification, structural characterization, safety evaluation, and translational development against MDROs.

A. Badawy, E. M. El-Fakharany, Jehan S. Albrahim et al. · 0 citations

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