Serum IGF-1 and IGFBP-3 Levels Before and After Induction Chemotherapy in Children with Acute Lymphoblastic Leukemia
Background: The growth hormone–insulin-like growth factor (GH–IGF) axis is suppressed by systemic inflammation and catabolism. We assessed the dynamics of Insulin-like Growth Factor-1 (IGF-1) and Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) in children with acute lymphoblastic leukemia (ALL) at presentation a...