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Author

A. Ballesteros-Tato

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Open access Oct 2026

IL-2-Producing Tfh Cells Sustain Treg Cell Homeostasis and Immune Tolerance in the Gut

Follicular helper T (TFH) cells are well known for their role in supporting B cell responses. Here, we identify a critical B cell-independent function for TFH cells in sustaining regulatory T (Treg) cells within gut-associated lymphoid tissues (GALT). We demonstrate that TFH cells produce interleukin-2 (IL-2) at the T...

Shivangi Dave, Holly Bachus, Nathan Santiago et al. · 1 citation

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