Open access
Sep 2026
Metabolic modeling with reverse mapping links host perturbations to Mycobacterium tuberculosis
Summary Understanding host-pathogen interactions during Mycobacterium tuberculosis (Mtb) infection has largely relied on identifying bacterial genes essential for intracellular survival. However, conventional reverse genetics approaches often overlook host pathways that regulate Mtb growth. Here, we developed a backtra...
Jayendrajyoti Kundu, Vishawjeet Barik, Abhijit Paul et al.
· iScience · 0 citations