Structural genome variation drives adaptation of the xylose-fermenting yeast Scheffersomyces stipitis to lignocellulosic hydrolysates
It is demonstrated that chromosome scale structural variation, rather than point mutations, underlies the improved phenotype of the evolved strains of Scheffersomyces stipitis and provides direct evidence that balanced rearrangements and minichromosome formation can be selected during prolonged stress and can generate...