Influence of dapagliflozin on cardiac remodeling in aortic stenosis rats: functional assessment and inflammatory and autophagic pathways evaluation
Sodium-glucose co-transporter 2 (SGLT2) inhibitors have beneficial effects in the treatment of heart failure with both preserved and reduced ejection fraction. However, their influence in patients with aortic stenosis-induced heart failure has not been established. In this study, we investigated the effects of th...