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Author

A. Cameron

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Open access Aug 2026

Dynamic inositol pyrophosphate synthesis is a targetable therapeutic opportunity in ovarian cancer

We previously reported that the phosphate exporter XPR1 is required to prevent toxic phosphate accumulation in ovarian cancer cells. To guide therapeutic development, we sought to systematically compare potential strategies to inhibit XPR1: directly targeting the phosphate efflux channel, targeting its partner protein...

Daniel P. Bondeson, David Husselbee, Saoirse Hanbury et al. · 0 citations

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