Open access
Sep 2026
H3K9ac promoter profiling and their association with gene expression in immune cells of T2-high asthma patients.
BACKGROUND Asthma is a heterogeneous chronic inflammatory syndrome, with the T2-high endotype defined by robust type 2 immune responses and skewed T helper polarization. Although H3K9 acetylation (H3K9ac) is a key activating histone mark in T helper differentiation, its genome-wide promoter landscape in circulating imm...
Daniel González, Alexis Infante, L. López-Kleine et al.
· Molecular Immunology · 0 citations