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A. Capstick

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Open access Sep 2026

Circulating extracellular vesicle lipidomics identifies distinct signatures of amyotrophic lateral sclerosis and spinal muscular atrophy

Amyotrophic lateral sclerosis (ALS) is a heterogeneous neurodegenerative disorder lacking established biomarkers of underlying disease biology. Here, we identify lipidomic signatures of circulating extracellular vesicles (EVs) that distinguish ALS from neurologically healthy controls and related neuromuscular diseases....

V. Ricotti, A. Fogel, M. van den Bosch et al. · 0 citations
#machine learning Preprint Sep 2026

RACER: Role-Aligned Competence Estimation for Human-AI Routing

Learning to defer asks a predictive system when to act autonomously and when to defer to a human expert. Population-adaptive deferral extends this problem to unseen experts using a small context set of expert behavior. Neural context encoders such as L2D-Pop can be query-dependent, but may learn routing shortcuts tied...

Joshua Strong, Emma Sun, A. Capstick et al. · 0 citations

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