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Review Aug 2026

Neurosurgical management of childhood-onset epilepsy in periventricular nodular heterotopia: A systematic review of effectiveness and outcomes.

Epilepsy associated with periventricular nodular heterotopia (PVNH) frequently begins in childhood and often proves refractory to medication. Surgical management is challenging, as lesions are frequently deep-seated or bilateral, and seizure onset often involves networks extending beyond the heterotopic tissue itself,...

Srishruthi Thirumalai, D. Champsas, M. L. Bianco et al. · 0 citations
Open access Aug 2026

Opposing associations of default mode network and subcortical network efficiency with IQ in children with drug-resistant epilepsy.

Paediatric drug-resistant epilepsy (DRE) is associated with IQ deficits only partially explained by clinical seizure variables (for example, age of onset, seizure burden, seizure location). Given that intelligence depends on efficient large-scale brain networks, structural connectomics provides a complementary mechanis...

Prithviraj Tawde, D. Velanoski, R. Piper et al. · 0 citations

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