The Achilles tendon enthesis rebuilds its mineralization front on reloading but retains a nanoscale imprint of unloading
The enthesis is a graded fibrocartilaginous interface that transfers load between tendon and bone, yet the nanoscale mechanisms stabilizing its mineralization front remain unclear. Here, we combine multimodal 2D/3D X-ray imaging with nonlinear optical microscopy to map structural, crystalline and extracellular matrix o...