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Á. Criollo-Rayo

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Case report Open access Aug 2026

First report of MUTYH-associated polyposis with c.1353_1355del and c.452A>G mutations in Tolima Grande region from Colombia: a case report

Introduction The MUTYH gene encodes a protein involved in DNA repair and is known for MUTYH-associated polyposis (MAP), a rare autosomal recessive condition that predisposes individuals to colorectal cancer (CRC), colorectal polyps and familial colorectal cancer syndrome. Case report We describe the first Tolima Grande...

Mabel E Bohorquez-Lozano, John Suarez-Olaya, Andrea Catalina Rubio-Vargas et al. · 0 citations
Open access Sep 2026

Runs of Homozygosity and Signatures of Positive Selection in Colombian Native American Populations: Genetic Architecture and Demographic History.

OBJECTIVES Runs of homozygosity (ROHs) are suitable for studying population demographic history. This study analyzed whole-genome patterns of homozygosity and natural selection in Colombian indigenous populations to identify their role in population structure and demographic history. MATERIALS AND METHODS Individuals...

Á. Criollo-Rayo, Catalina Rubio-Vargas, Carlos Puentes et al. · 0 citations

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