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Sep 2026

Unanticipated global emergence and evolution of Pneumocystis jirovecii mutations and resistance driven by a human-targeted drug.

Nearly all known cases of antimicrobial resistance have been linked to agents that directly target microbes. This paradigm overlooks other drivers of microbial evolution and resistance. Here, we report compelling evidence of resistance-associated mutations in Pneumocystis jirovecii, a high-priority fungal pathogen desi...

Liang Ma, Ming Hao, Wei-Zhong Chang et al. · 0 citations
Sep 2026

Two Distinct Outbreaks of Extended-spectrum Beta-lactamase-producing Klebsiella Species in a Neonatal and Pediatric Intensive Care Unit in Switzerland.

BACKGROUND Healthcare-associated infections caused by Klebsiella spp. are associated with substantial morbidity and mortality in neonatal and pediatric intensive care units. We describe 2 outbreaks of extended-spectrum beta-lactamase-producing Klebsiella michiganensis and Klebsiella pneumoniae in the same unit. METHO...

Cornelia Kirchner, Laura Werlen, C. Guler et al. · 0 citations

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