Author

A. Dale

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Open access Sep 2026

Early-childhood temperament trajectories map onto transdiagnostic psychiatric risk.

Early-childhood temperament is associated with later mental health. Temperament continues to develop throughout the first years of life, and a single assessment cannot capture its trajectory. Whether departures from an individual's developmental trajectory carry psychiatric risk remains unknown. Using data from more th...

J. Kopal, N. Bakken, P. Parekh et al. · Molecular Psychiatry · 0 citations

Open access Aug 2026

An Integrative Multimodal Model for Early Diagnosis of Dementia and Differential Diagnosis of Alzheimer's Disease Using Neuroimaging, Polygenic Risk, and Cognitive Assessments

Multimodal integration of cognitive, neuroimaging, and polygenic data in the MHS-RWD tool yields strong discrimination for both early diagnosis of dementia and AD differential diagnosis, which could support etiologically informed dementia decisions in real-world settings, with potential utility in primary care.

T. T. Filiz, V. Fominykh, K. Persson et al. · medRxiv · 0 citations

Open access Sep 2026

Molecular Underpinnings of Retinal Traits 1 Shared with Major Psychiatric Disorders

Recent large-scale studies have enabled new knowledge about genetic underpinnings of morphological and electrophysiological alterations of the retina. Variation in retinal traits, often of neurodevelopmental origin, have been linked to major psychiatric disorders (MPDs). Here, we investigate the genetic overlap between...

P. Jahołkowski, N. Parker, I. Sveen et al. · medRxiv · 0 citations