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Open access Sep 2026

Influence of increased injected activities up 9.0 GBq [177Lu]Lu-PSMA-I&T on absorbed doses to lesions and kidneys

Administration activities of 177Lu-PSMA were chosen cautiously in the treatment of advanced prostate cancer. The primary aim was to investigate the association between increased injected activities, and the calculated absorbed doses (AD). In this single center, retrospective analysis, patients with PSMA-avid metastatic...

Z. Ells, Linus Hempel, J. Ells et al. · 0 citations
Open access Oct 2026

Long-term effects of [177Lu]Lu-PSMA therapy on the kidneys based on cumulative absorbed dose

177 Lu-PSMA radiopharmaceutical therapy shows favorable clinical responses for metastatic castration-resistant prostate cancer patients but may cause radiation-induced kidney damage due to specific and nonspecific activity accumulation. We evaluated the association between cumulative kidney absorbed doses and...

Z. Ells, Mu-Yu Wu, Linus Hempel et al. · 0 citations

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