Human leukocyte antigen (HLA) molecules mediate peptide presentation and shape immune recognition, with clinical relevance well beyond donor-recipient matching. This review describes how HLA variation and anti-HLA immunity affect transfusion medicine, autoimmune and infectious diseases, pharmacogenomics, cancer, pregna...
Saikat Mandal, Joyisa Deb, Aswin K. Mohan et al.· Frontiers in Immunology· 0 citations
Objectives: Pancreatitis is the third leading cause of gastrointestinal disease-related hospitalization. Pancreatitis burden has continued to increase since 1990, with trends driven by changing exposures to risk factors, population growth, and population aging. We report the national- and state-level estimates of pancr...
M. M. Reddy, Anish Chopra, G. Aswath et al.· Journal of Clinical Medicine· 0 citations
Objectives: Upper gastrointestinal bleeding (UGIB) is a common medical emergency associated with substantial morbidity and mortality. Several clinical risk scores are available, but their comparative performance across outcomes and patient subgroups remains uncertain. We compared five established UGIB risk scores for p...
Mohamed Jalloh, Balamrit Singh Sokhal, Maryam Javed et al.· Journal of Clinical Medicine· 0 citations
Background: We examined temporal trends in deaths mentioning both pancreatic cancer and renal failure in the United States. Methods: We analyzed CDC WONDER multiple-cause-of-death data for adults aged ≥25 years from 1999 to 2024. Age-adjusted mortality rates (AAMRs) were assessed using Joinpoint regression. Secondary a...
A. Dhali, Ali Shan Hafeez, J. Biswas et al.· Epidemiologia· 0 citations
Findings should be interpreted as hypothesis-generating rather than definitive evidence of superiority or equivalence, but larger, prospective, multi-centre studies with standardised outcome definitions and robust adjustment for confounding are needed to clarify the comparative clinical and cost-effectiveness of roboti...
H. Bharadwaj, E. Danda, S. H. Ali et al.· Medical Science· 0 citations
Mortality involving pancreatic cancer and PE increased substantially in the United States, and PE was recorded in a growing proportion of pancreatic cancer deaths, and PE was recorded in a growing proportion of pancreatic cancer deaths.
A. Dhali, J. Biswas, Ali Shan Hafeez et al.· Diseases· 0 citations
A narrative review synthesizes evidence published between 2020 and 2026 within a unified clinical framework not provided by prior reviews, and proposes an original biomarker-guided clinical algorithm, a comparative clinical readiness table, and a disease-continuum biomarker timeline as practical tools for clinicians an...
Ashish Sharma, J. Tan, Rajvardhan Sisodia et al.· Frontiers in Oncology· 0 citations
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