Potential role of 5-HT7 receptor antagonists in the treatment of depression: Pharmacological and bioengineering perspectives.
PURPOSE OF REVIEW Targeting serotonergic receptors, as well as the serotonin uptake, is a relevant treatment approach for the treatment of depression. The 5-hydroxytryptamine 7 receptor (5-HT7R) is a G-protein coupled receptor belonging to the serotonergic receptor family, which has received a lot of attention due to i...