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Current evidence linking the microbiome-gut-brain axis to glioma development, progression, and treatment response is summarized, highlighting findings from human studies, preclinical models, and recent mechanistic investigations.
The utility of ctDNA, particularly CSF ctDNA, as a complementary diagnostic tool in neuro-oncology is supported, with a promising performance of ctDNA analysis in patients with diffuse gliomas as a liquid biopsy strategy.
A retrospective multi-institutional cohort study including 296 patients from 13 centers, SRS achieved durable long-term control with favorable survival and low incidence of visual and endocrinologic dysfunction.
With gravity-based retraction, modern navigation, and functional mapping, DMFC lesions can be resected more safely than in the past and support redefining SMA syndrome and expanding the role of mapping-guided resections in this region.
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