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Case report Open access Sep 2026

A POLE P286R‐Mutated Hepatoid Adenocarcinoma of the Lung Showing Substantial Response to Immune Checkpoint Inhibition

Hepatoid adenocarcinoma of the lung (HAL) is a rare form of lung cancer with histological and morphological properties of hepatocellular carcinoma, characterized by an aggressive course of the disease and unfavorable prognosis. Given the rarity of the pathology and the lack of unambiguous therapeutic protocols, descrip...

A. Chernev, A. Kaurtseva, R. Abasov et al. · 0 citations
Open access Sep 2026

Molecular Profile of Extracranial Solid Tumors in Children: Diagnostic and Therapeutic Opportunities

Introduction: Despite the relatively low mutational burden of most pediatric tumors, molecular genetic studies are increasingly being used in pediatric oncology. They enable confirmation of diagnosis, assessment of prognosis, and identification of potential targets for molecularly targeted therapy. Analysis of molecula...

Nataliya Andreeva, T. Shamanskaya, A. Druy et al. · 0 citations

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