Open access
Oct 2026
Impact of higher comorbidity burden on guideline-directed medical therapy in patients with heart failure with reduced ejection fraction
Patients with a higher comorbidity burden less often used quadruple therapy and had a worse prognosis, as well as its association with clinical outcomes, according to a prespecified subanalysis of the TITRATE-HF registry.
J. J. N. Krabbe, M. I. Wilde, A. Mosterd et al.
· European Heart Journal · 0 citations