Author

A. Elshamy

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Oct 2026

Polyphenol-rich Salsola imbericata extract attenuates experimental lung injury via modulating oxidative stress, NLRP3 inflammasome activation and apoptosis singling.

Salsola imbericata is a halophytic plant with promising yet underexplored pharmacological potential. The present study aimed to characterize the metabolite profile of its ethanolic extract (SI-EtOH) and evaluate its protective effects against experimentally induced lung injury. UPLC-PDA-ESI-TOF-MS/MS-based metabolomics...

Asmaa S. Abd Elkarim, Rania F. Ahmed, I. Younis et al. · Tissue & Cell · 0 citations

Aug 2026

Alogliptin mitigates doxorubicin-induced cardiotoxicity in rats: Implications of SIRT3/NRF2 pathway and miRNA-133a.

Present results proved the prophylactic ALO antioxidant, anti-inflammatory, anti-apoptotic, and anti-fibrotic influence on the DOX-induced cardiotoxicity with proposed mechanisms entailing the activation of SIRT3 pathway that may be governed by miRNA-133a.

N. F. Elmongy, Mohamed Ali Abbas, S. Elshora et al. · Tissue & Cell · 0 citations

Open access Aug 2026

Guazuma ulmifolia butanol extract protects against cadmium-induced hepatotoxicity via HO-1/Sirt-1 activation, miRNA–lncRNA modulation, and metabolic reprogramming

Gul-BuOH affords dose-dependent protection against Cd-induced liver injury by modulating oxidative stress, inflammation, metal detoxification, and metabolic pathways, supporting the traditional use of G. ulmifolia and its potential as a multi-target hepatoprotective agent.

O. A. Elsabagh, Abdelbaset M. Elgamal, Heba A. Hassan et al. · PLoS ONE · 0 citations