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Open access Sep 2026

Cross-platform, multi-cohort identification of a caries microbial signature

Abstract Objective To identify a robust salivary microbial signature associated with caries using a cross-platform, multi-cohort design. Design Full-length 16S rRNA gene sequencing (ONT) and shotgun metagenomics (MET) were performed in a derivation cohort with matched data (n = 463). Associations between the oral micro...

A. Esberg, Daniel Jönsson, Peter Persson et al. · 0 citations
Open access Sep 2026

Life stage shifts in salivary microbiota determinants: a cross-sectional study in twins

Both host genetics and environmental exposures shape the salivary microbiota; however, the relative contributions of these factors from early life to adulthood remain unclear. To address this, we profiled the salivary microbiota of 3387 twin pairs: 939 infant pairs (9–12 months) and 2,448 adult pairs (23–52 years) usin...

Simon Haworth, E. Bellou, R. Kuja-Halkola et al. · 0 citations

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