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Author

A. Fabrizi

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Review Open access Sep 2026

Living scaffolds in monogenic genodermatoses: 3D skin models for physiopathology, gene therapy, and drug testing.

Keratinocytes have been cultured in vitro for more than 50 years to produce long-lasting epithelial grafts containing stem cells, transient amplifying progenitors, and differentiated cells. They have been widely used to study the molecular mechanisms underlying skin physiology, pathology (e.g. functional alterations ca...

G. Bergamini, Gaia Andrea Gozza, A. Fabrizi et al. · 0 citations
Review Open access Aug 2026

Gene therapy for genodermatoses at the crossroads of innovation and clinical translation

The biological and regulatory challenges that need to be overcome are examined to bridge the gap between experimental innovation and clinically accessible therapies for patients with inherited skin diseases.

A. Fabrizi, Marta Valenti, Silvia Zacchino et al. · 0 citations

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