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Author

A. Farolfi

3 papers indexed here

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Clinical trial Open access Oct 2026

PIK3CA Mutations in Advanced or Recurrent Endometrial Cancer: An Exploratory Molecular Profiling From the Phase II MITO END-3 Study.

PURPOSE Immunotherapy with chemotherapy significantly improves progression-free survival in advanced endometrial cancer (EC), especially in microsatellite instability-high (MSI-H) cases. Despite this, for recurrent EC in the postimmunotherapy setting, new treatment options are urgently needed. The PI3K pathway is frequ...

A. Passarelli, G. L. Scaglione, D. Califano et al. · 0 citations
Review Open access Sep 2026

Advancing therapies for HER2-positive metastatic breast cancer: Navigating a wealth of treatment options.

The therapeutic landscape of HER2-positive metastatic breast cancer (HER2-positive mBC) has been transformed by increasingly effective HER2-directed therapies. Following the establishment of trastuzumab and pertuzumab as first-line standard treatment, highly active antibody-drug conjugates (ADCs), particularly trastuzu...

M. Palleschi, A. Viansone, Filippo Merloni et al. · 0 citations
Review Open access Sep 2026

Quality of life in first-line trials for endometrial cancer: A systematic review.

OBJECTIVE As treatment strategies evolve in advanced or metastatic endometrial cancer (EC), quality of life (QoL) has become a key parameter in evaluating therapeutic value. This systematic review summarizes QoL outcomes from pivotal trials that have shaped clinical practice in advanced EC. METHODS Data from phase II...

V. Tuninetti, A. Farolfi, Simona Butticè et al. · 0 citations

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