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A. Fatatis

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Mechanistic insights into the regulation of pro-metastatic IL-1[beta] expression by androgen receptor in prostate cancer cells

A mechanistic framework is established linking AR signaling, JAK2/STAT1 activation, cathepsin B-dependent IL-1[beta] processing, and paracrine cytokine signaling in metastatic CRPC while identifying IL-1[beta] signaling as a potential therapeutic target in advanced prostate cancer.

Y. Oyende, A. Fatatis · 0 citations

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