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Sep 2026

New 1,3,4-oxadiazole derivatives as potential anticancer agents against esophageal cancer: Synthesis, biological evaluation, molecular docking, and density functional theory study

Four new 1,3,4-oxadiazole derivatives (L1-L4) were synthesized through a four-step synthetic pathway involving hydrazide formation, cyclization to the 1,3,4-oxadiazole ring, hydrazination, and hydrazone formation by condensation with appropriate aldehydes. Their anticancer potential against esophageal adenocarcinoma (S...

A. Fazaa, Ibrahim A. Flifel, Alyaa Majid · 0 citations

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