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Author

A. Foudah

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Review Open access Aug 2026

Phytochemical Profile and Pharmacological Potentials of Solanum dubium (Fresen.)

Solanum dubium Fresen. is a species of the Solanaceae family. It is an indigenous wild plant of Sudan and other East African countries. The aim of this review is to explore and analyze its phytochemical constituents and pharmacological activities. The review followed the Preferred Reporting Items for Systematic reviews...

Wadah Osman, Mohamed Mirghani, Aisha Mohamed Kosar et al. · 0 citations
Open access Sep 2026

LC-MS/MS profiling and evaluation of antibacterial and antibiofilm activities of Conocarpus lancifolius phenolics against Acinetobacter baumannii

Acinetobacter baumannii is a clinically significant pathogenic bacterium known for its ability to form biofilms. Few studies have comprehensively investigated the chemical composition of Conocarpus lancifolius growing in Saudi Arabia. Here, we investigated the LC-MS/MS (liquid chromatography-tandem mass spectromet...

F. A. Abdel Bar, Amirat A. Al-Sabeely, E. Elekhnawy et al. · 0 citations
Sep 2026

Exploiting sulfur transfer machinery in Mycobacterium tuberculosis: Discovery of novel CysA2-directed antitubercular leads.

The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains highlights the requirement for new therapeutic targets and antitubercular chemotypes. CysA2, a sulfur transferase that participates in sulfur metabolism and redox homeostasis, is a relatively underexplored...

A. Foudah, Mohd Imran, Mohd Saeed et al. · 0 citations
Review Aug 2026

Purine-centred fused, conformationally constrained, and ring-expanded analogues in antitumor and antiviral drug discovery: A comprehensive review.

Purine-derived scaffolds remain important in anticancer and antiviral drug discovery because their electronic properties, hydrogen-bonding capacity, and conformational adaptability support interactions with kinases, polymerases, nucleotide-processing enzymes, and nucleic acids. This review critically examines three maj...

Manisha Nidhar, P. Alam, M. Alqarni et al. · 0 citations
Oct 2026

Development and Optimization of Baicalin-Loaded Transniosomes Using Quality by Design: Dermatokinetic and In Vivo Efficacy Evaluation.

OBJECTIVE This study aimed to develop and optimize a baicalin-loaded transniosomal gel (BCL-TN) to enhance the dermal delivery and therapeutic efficacy of baicalin for the management of skin cancer. SIGNIFICANCE Baicalin possesses potent anticancer activity but exhibits poor skin permeability, which limits its clinic...

Alhussain H. Aodah, Bjad K. Almutairy, A. Foudah et al. · 0 citations
Open access Sep 2026

Formulation and In Vitro Evaluation of Meloxicam-Loaded Transdermal Patches: Effect of Polymeric Blends on Drug Release and Kinetics

Findings highlight the influence of polymeric composition on drug release behavior and support the potential of transdermal systems as an alternative to oral meloxicam therapy.

Ameen M. Alwossabi, Imad M. Taj Eldin, A. M. Al-Ghani et al. · 0 citations
Jul 2026

Structure-Based identification of potent dengue virus RNA-dependent RNA polymerase inhibitors using integrated computational workflow

An integrated computational workflow was applied to identify potential inhibitors of dengue virus RNA-dependent RNA polymerase (RdRp) after screening of approximately 9,900 bioactive compounds through structure-based virtual screening and molecular docking, supporting these compounds as promising RdRp inhibitors.

T. M. Aljarba, A. Alam, Gopal Prasad Agrawal et al. · 0 citations
Open access Jul 2026

Greenness, blueness, and whiteness profiles of HPTLC method for the simultaneous assay of tenofovir and emtricitabine in fixed-dose combination dosage forms

A sustainable reverse-phase HPTLC methodology for determining TEN and ECT concurrently in their fixed-dose combination (FDC) products is developed and verifies and suggested that the recommended method may be applied to precisely evaluate TEN and ECT in commercial formulations.

P. Alam, Faiyaz Shakeel, M. Alqarni et al. · 0 citations

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