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Open access Feb 2026

Dual antithrombotic therapy with dabigatran and ticagrelor in patients with acute coronary syndrome and non-valvular atrial fibrillation undergoing percutaneous coronary intervention (ADONIS-PCI): protocol for a randomized controlled pilot trial

Introduction Patients with atrial fibrillation (AF) presenting with acute coronary syndrome (ACS) and undergoing percutaneous coronary intervention (PCI) require protection against both cardioembolic and coronary thrombotic events, while facing a substantial bleeding risk. Oral anticoagulation (OAC) reduces the risk of...

M. Jaguszewski, Aleksandra Gąsecka-van der Pol, Natasza Gilis-Malinowska et al. · 0 citations
Open access Aug 2026

Clinical characteristics associated with failure to achieve a prespecified guideline-directed medical therapy target at discharge in patients with HFrEF undergoing scheduled hospitalization: a secondary analysis of the HEROES study

Guideline-directed medical therapy (GDMT) is crucial for the pharmacological management of heart failure (HF) with reduced ejection fraction (HFrEF). The aim of the study was to identify clinical characteristics associated with failure to achieve the prespecified stringent GDMT target in patients with HFrEF undergo...

A. Galas, R. Morawiec, I. Gorczyca-Głowacka et al. · 0 citations

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