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A. Gambadoro

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Open access Aug 2026

Primary Ciliary Dyskinesia from Embryogenesis to Adulthood: Micro-CT Analysis of Stage-Dependent Upper Airway Abnormalities in Odad3 Loss-of-Function Mouse Models

Background/Objectives: Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder characterized by impaired ciliary function, leading to chronic airway disease. Loss-of-function mutations in ODAD3 (CCDC151) represent an established cause in patients, and Odad3-deficient mice recapitulate key disease trait...

Tiziana Orsini, S. Putti, F. Chiani et al. · 0 citations

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