Author

A. Giudetti

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Open access Jul 2026

Oleoylethanolamide attenuates early skeletal muscle metabolic remodeling induced by short-term high-fat diet exposure.

Findings identify skeletal muscle as an early target of fat-induced metabolic dysfunction and support further investigation of OEA as a promising pharmacological strategy to intercept obesity-associated metabolic deterioration before overt obesity develops.

M. Friuli, B. Eramo, N. Zahid et al. · Pharmacological Research · 0 citations

Open access Aug 2026

Persistent lipotoxicity overwhelms adaptive capacity in human hepatic cell line.

Sustained PA/OA exposure induces a staged hepatocellular response, early lipid-buffering adaptation, intermediate metabolic compensation, and late decompensation, indicating that chronic lipotoxicity reflects progressive loss of regulatory coordination despite persistent metabolic adaptation.

I. Serra, Elisa Bisconti, Francesco Vari et al. · Journal of NutriLife · 0 citations