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A. Grell

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Open access Jun 2026

Zerumbone alleviates TRESK- and TRPV1-mediated ion currents and reduces excitability of human iPSC-derived nociceptor-like neurons.

Secondary plant metabolites are widely used in traditional and naturopathic medicine to treat pain, infection, and inflammation. The sesquiterpenoid zerumbone, derived from the edible ginger Zingiber zerumbet, has been shown to exert analgesic, antioxidant, antitumoral, and antimicrobial effects in preclinical models,...

Naomi Hoerdler, A. Grell, Saheli Chatterjee et al. · 0 citations

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