Open access
Sep 2026
Massively parallel functional profiling prioritises breast cancer risk variants and implicates CCDC88C in ER-positive breast cancer.
This work identified 709 variants mapping to 140 risk regions, that are associated with significant variation between REF and ALT alleles, that may influence breast cancer risk through expression of CCDC88C, which in turn could impact prognosis.
Kate Mackie, H. Kemp, A. Gunnell et al.
· HGG advances · 0 citations