Author

A. Guss

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Open access Jul 2026

A Fourier-based global denoising model for the smart removal of artifacts in microscopy images

A global denoising model (GDM) to smartly remove artifacts from microscopy images while preserving weaker but physically important features is proposed and the tuning effect between two imaging input channels on the trade-off performance between artifact removal and feature preservation is showcased.

Huan-Huan Zhao, Connor Vernachio, Laxmi Bhurtel et al. · Machine Learning: Science an... · 0 citations

Open access Jul 2026

Pathway selection for arabinose utilization in Pseudomonas putida reveals a rate-yield tradeoff in muconic acid production from lignocellulosic sugars

This study presents a systematic comparison of sugar catabolic pathways that enabled development of strains suited for the tradeoffs between rate and yield and indicates that these performance metrics can reduce the minimum selling price of muconate-derived adipic acid and greenhouse gas emissions.

Dowan Kim, Torrey M Lind, Chen Ling et al. · bioRxiv · 1 citation

Open access Jul 2026

Simultaneous optimization of lignocellulosic sugar catabolism via systematic laboratory evolution under complex selection pressure

Efficient co-utilization of hexose and pentose sugars from lignocellulose is essential for microbial bioconversion, yet engineered catabolic pathways can be unstable or suboptimal in complex resource environments. Here, we use a Pseudomonas putida strain engineered to catabolize xylose and arabinose to examine how reso...

Sunghwa Woo, H. Lim, B. Norton-Baker et al. · Nature Communications · 0 citations