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Review Sep 2026

Comprehensive evaluation of analytical methods for determination of ansamycins across diverse matrices.

Ansamycins (ANs), including rifampicin (RIF), rifabutin (RFB), rifapentine (RPT), rifalazil (RFL), and rifaximin (RFX), are structurally distinctive macrocyclic antibiotics whose analytical determination is complicated by very low systemic exposure (especially RFX), high protein binding and intracellular sequestration...

H. Barzani, R. Omer, A. H. Mer et al. · 0 citations

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