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A. Haghparast

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Oct 2026

The effect of concurrent application of the deep brain stimulation of the nucleus accumbens and cannabidiol injection during extinction period on reinstatement of METH-induced conditioned place preference in extinguished rats.

Methamphetamine (METH) is a potent stimulant drug that significantly alters the function of the central nervous system (CNS). METHS's abuse may be linked with a variety of psychiatric disorders, primarily by affecting the reward system. Cannabidiol (CBD), a primary cannabinoid component of the Cannabis plant, has been...

Mahsa Mohammadi, M. Zendehdel, A. Haghparast · 0 citations
Open access Aug 2026

Oscillatory activity and LFP power modulation in the hippocampal CA1 and prelimbic cortex during morphine-induced place preference

Morphine use disorder (MUD) is a complex neurobiological condition characterized by the reinforcement of addictive behaviors and the development of both psychological and physical dependence. The euphoric effects induced by morphine are mediated by key brain regions, including the CA1 region of the hippocampus and the...

Fazel Moshrefi, Amir Mohammad Farrokhi, Habib Karimian-Sani-Varjovi et al. · 0 citations
Sep 2026

Cannabidiol modulates the brain rhythms within the hippocampal-prelimbic pathway in reinstatement of extinguished methamphetamine-induced conditioned place preference.

Insight is offered into neural mechanisms of drug-induced reinstatement, highlighting CBD's potential for managing addiction-related brain oscillations and guiding future research on addiction intervention strategies.

Reyhaneh Ghasab Sedehi, Saeideh Karimi-Haghighi, Etrat Hooshmandi et al. · 0 citations
Aug 2026

Modulatory role of the mPFC orexin-2 receptors in the acquisition and expression in two paradigms of the natural- and drug-induced conditioned place preference in the rats.

A differential involvement of mPFC Orx2Rs in the acquisition and expression phases of CPP is proposed, suggesting distinguishable behavioral effects between food and morphine reward models, however, further mechanistic studies are required to clarify the underlying neural substrates.

S. Jamali, Mahboobeh Mirmohammadi, Ronak Azizbeigi et al. · 0 citations

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