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A. Hessell

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Open access Aug 2026

Comparison of Systemic and Mucosal Synchronous Immunization with Replicating Single-cycle Adenoviruses and SOSIP Protein HIV-1 Vaccines

Synchronous immunizations of rhesus macaques with gene-based replicating single-cycle adenovirus expressing SIV gag and clade C gp160 envelope, and SOSIP clade C envelope protein vaccine suggest vaccination at the mucosal portal of infection provides better localized protection against incoming SHIV and perhaps HIV-1.

P. Nehete, B. Nehete, Kathryn A. Shelton et al. · 0 citations
Review Open access Jul 2026

An HIV V1V2 mRNA-LNP vaccine induces strong, cross-clade functional antibody responses in mice and rhesus macaques 2307530

The V1V2 mRNA-LNP vaccine is highly immunogenic in mice and rhesus macaques, eliciting cross-clade functional antibodies capable of recognizing native Env, and may provide insights relevant to vaccine testing against other pathogens.

Catarina E. Hioe, Xiao-Mei Liu, C. Yengo et al. · 0 citations

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