Author

A. Issabek

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Open access Sep 2026

OPTIMIZATION OF REFOLDING CONDITIONS FOR RECOMBINANT OMP19 PROTEIN FROM BRUCELLA SPP.

The recombinant Omp19 protein of Brucella spp. is considered as a promising antigen for the development of diagnostic test systems and immunobiological preparations. However, obtaining its soluble form remains a significant challenge. The aim of this study was to optimize the dialysis conditions for the recombinant Omp...

Гулнора Шухратбековна Адилова, O. Chervyakova, A. Issabek et al. · Biosafety and Biotechnology · 0 citations

Open access Aug 2026

The influence of cultivation parameters on the reproduction of recombinant influenza viruses expressing immunodominant proteins of Mycobacterium bovis.

INTRODUCTION Influenza A virus is considered a promising vector platform for the creation of recombinant vaccines due to its high immunogenicity and ability to induce a pronounced humoral and cellular immune response. The aim of the study is to investigate the optimal cultivation parameters for recombinant influenza A...

R. Abitayev, A. Issabek, A. Nurpeisova et al. · Voprosy virusologii · 0 citations