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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

A. Iyaswamy

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Review 2026

The Tau-mitochondria connection and its impact on cellular energy metabolism in Alzheimer's disease.

This chapter looks at the nature of the tau-mitochondrial interface, and proposes a paradigm of tau-induced energy failure in AD, and discusses novel therapeutic approaches that target both tau and mitochondrial abnormalities, namely antisense oligonucleotides (ASO), mitochondria targeted compounds and mitophagy modifi...

Abhay Kumar Singh, Supraja M. R., Amal P. S. et al. · 0 citations
Open access Sep 2026

Gomisin N ameliorates autophagy-neuroinflammation imbalance in Parkinson's disease models via modulating the ATG16L1/NLRP3 axis.

GN is a brain-penetrant preclinical candidate that links ATG16L1-dependent autophagy with α-synuclein clearance and NLRP3 inflammasome suppression in PD models and completely abrogated the neuroprotective and anti-inflammatory effects of GN both in vitro and in vivo.

Cheng-Fu Su, Zhi-Qiang Deng, Ka-Yee Ying et al. · 0 citations
Review Open access Aug 2026

New insights on microglial lysosomal acidification: A therapeutic target of neurodegenerative diseases.

Restoration of microglial lysosomal acidification represents a promising therapeutic strategy for neurodegenerative diseases and a prognostic biomarker for disease progression and therapeutic response.

R. Jaganathan, Srilakshmi Vijayakumar, Yinchi Chen et al. · 0 citations

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